Medication-Related Osteonecrosis of the Jaw: A Brief Overview

Antiresorptive drugs such as bisphosphonates (BP) and denosumab are primarily utilized in the treatment of osteoporosis and certain cancers in bone (e.g. multiple myeloma) or metastatic cancers to the bones (e.g. breast, prostate, colon, lung). Treating patients with a history of BP or denosumab therapy in the dental setting can have potentially serious complications, particularly bisphosphonate-related osteonecrosis of the jaw (BRONJ) or medication-related osteonecrosis of the jaw (MRONJ). Assessment of ...
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